GAK

Across TCGA cell cohorts, GAK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,391 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GAK-associated GO terms across cancer lineages are Clathrin coat disassembly, Transcription pausing by RNA polymerase II, and Cellular response to bile acid. Each is linked with GAK in more than 18 cancer types. Because this analysis shows association rather than direction, both GAK-to-partner and partner-to-GAK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Clathrin coat disassembly grouped by GAK-low versus GAK-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAK→partner) and Y-score (partner→GAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Clathrin coat disassembly →	+0.221	+1.054	<.001	<.001	3	19
BONE	Transcription pausing by RNA polymerase II →	+0.180	+0.845	<.001	<.001	3	18
OVARY	Cellular response to bile acid →	+1.076	+0.983	<.001	<.001	3	16
OESOPHAGUS	Vesicle uncoating →	+0.175	+1.143	<.001	.004	3	16
BONE	Regulation of aggrephagy →	+0.205	+1.184	<.001	<.001	3	15
OVARY	Glycerophospholipid metabolic process →	+0.041	+0.919	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,391 associations by consensus.

Clathrin coat disassembly by GAK expression — URINARY_TRACT

Explore this box plot interactively →