GAGE2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAGE2A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible GAGE2A-associated genes across cancer lineages are RNA5SP426, RNA5SP234, and MIR489. Each is linked with GAGE2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE2A-to-partner and partner-to-GAGE2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE2A→partner) and Y-score (partner→GAGE2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP426 →+0.318+7.924<.001.00831
LUSCRNA5SP234 →+0.455+7.924<.001.00831
LUSCMIR489 →+0.420+7.924<.001.00831
LUSCRNA5SP31 →+0.705+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration