GAGE12C

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAGE12C RNA expression is significantly associated with the mutation status of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GAGE12C-associated genes across cancer lineages are KCNA1, FKBP11, and IER2. Each is linked with GAGE12C in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE12C-to-partner and partner-to-GAGE12C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNA1 grouped by GAGE12C-low versus GAGE12C-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE12C→partner) and Y-score (partner→GAGE12C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMKCNA1 →+4.173+0.020.003<.00131
SKCMFKBP11 →+7.816+0.204.008<.00131
SKCMIER2 →+7.816+0.204.008<.00131
SKCMAMY2B →+5.232+0.039<.001<.00131
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KCNA1 by GAGE12C expression — SKCM

Box plot of KCNA1 in GAGE12C-low vs GAGE12C-high samples in SKCM.

Explore this box plot interactively →

Exploration