GAGE12C

Across TCGA cell cohorts, GAGE12C RNA expression is significantly associated with the mutation status of many other genes, with 110 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GAGE12C-associated genes across cancer lineages are CCDC141, RNF112, and GPR161. Each is linked with GAGE12C in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE12C-to-partner and partner-to-GAGE12C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC141 grouped by GAGE12C-low versus GAGE12C-high in CNS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE12C→partner) and Y-score (partner→GAGE12C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCDC141 →	+4.035	+0.508	.006	<.001	3	2
LUNG_NSCLC_LUAD	RNF112 →	+5.228	+1.371	.005	.001	3	2
LUNG_NSCLC_LUAD	GPR161 →	+5.228	+2.203	.005	<.001	3	2
OVARY	LRIT1 →	+4.807	+0.330	.003	<.001	3	2
BLOOD_Myeloma	CHRNA4 →	+3.906	+2.381	.009	<.001	3	1
BLOOD_Lymphoma	CHRDL1 →	+5.643	+0.462	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

CCDC141 by GAGE12C expression — CNS

Explore this box plot interactively →