GADD45A

Across TCGA patient cohorts, GADD45A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GADD45A-associated proteins across cancer lineages are JUN, ANXA2, and LUZP1_S57. Each is linked with GADD45A in more than 4 cancer types. Because this analysis shows association rather than direction, both GADD45A-to-partner and partner-to-GADD45A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GADD45A versus JUN in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45A→partner) and Y-score (partner→GADD45A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	JUN →	+0.399	+1.144	<.001	<.001	3	4
GBM	ANXA2 →	+0.565	+0.867	<.001	<.001	2	5
BRCA	LUZP1_S57 →	+0.611	+0.795	.002	.008	3	4
OV	OSBPL9 →	+0.197	+0.527	.001	.005	3	4
BRCA	BRPF1_S460 →	-0.431	-0.867	<.001	<.001	3	4
OV	C12orf45_S178 →	-1.178	-0.824	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,977 associations by consensus.

GADD45A vs JUN — GBM

Explore this scatter interactively →