GAD2

Across TCGA patient cohorts, GAD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,036 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GAD2-associated proteins across cancer lineages are MAP2_S1790, PPP1R1A, and CACNA1A_S2464. Each is linked with GAD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAD2-to-partner and partner-to-GAD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAD2 versus MAP2_S1790 in HNSC, with a Pearson correlation of 0.21.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAD2→partner) and Y-score (partner→GAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAP2_S1790 →	+0.818	+0.183	<.001	.002	3	3
PDAC	PPP1R1A →	+0.668	+0.982	<.001	<.001	3	3
GBM	CACNA1A_S2464 →	+1.166	+1.744	<.001	<.001	3	2
BRCA	DECR2 →	-0.351	-0.037	.007	.004	3	2
CCRCC	PARN_S163 →	+0.630	+0.113	<.001	<.001	3	2
GBM	ASPH →	-0.443	-1.084	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,036 associations by consensus.

GAD2 vs MAP2_S1790 — HNSC

Explore this scatter interactively →