GAD2

Across TCGA cell cohorts, GAD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,171 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GAD2-associated GO terms across cancer lineages are Regulation of chromosome organization, Adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Regulation of myoblast fusion. Each is linked with GAD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAD2-to-partner and partner-to-GAD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by GAD2-low versus GAD2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAD2→partner) and Y-score (partner→GAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of chromosome organization →	+0.056	+0.008	.001	.008	3	3
BLOOD_Lymphoma	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.055	-0.008	.007	.008	3	3
LUNG_SCLC	Regulation of myoblast fusion →	+0.064	+1.938	.001	<.001	3	3
LUNG_SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.075	+1.765	<.001	.002	3	3
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.073	+1.980	<.001	<.001	3	3
LUNG_SCLC	Negative regulation of stem cell differentiation →	+0.191	+2.027	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,171 associations by consensus.

Regulation of chromosome organization by GAD2 expression — BLOOD_Lymphoma

Explore this box plot interactively →