GABRR2

Across TCGA patient cohorts, GABRR2 mutation is significantly associated with the RNA expression of many other genes, with 2,891 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRR2-associated genes across cancer lineages are RN7SL248P, RNU6ATAC30P, and VTRNA2-2P. Each is linked with GABRR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GABRR2-to-partner and partner-to-GABRR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by GABRR2-low versus GABRR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRR2→partner) and Y-score (partner→GABRR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.057	+3.137	<.001	.005	3	3
UCEC	RNU6ATAC30P →	+0.407	+2.379	<.001	<.001	3	3
CESC	VTRNA2-2P →	+0.404	+4.601	<.001	.004	3	2
UCEC	RPS29P32 →	+0.467	+2.277	<.001	.003	3	2
UCEC	HMX2 →	+1.185	+2.595	<.001	<.001	3	2
UCEC	TRAJ21 →	+0.468	+2.351	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,891 associations by consensus.

RN7SL248P by GABRR2 expression — UCEC

Explore this box plot interactively →