GABRQ

Across TCGA cell cohorts, GABRQ RNA expression is significantly associated with the go_rna of many other GO terms, with 1,883 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABRQ-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Regulation of protein modification by small protein conjugation or removal, and Transcription initiation at RNA polymerase II promoter. Each is linked with GABRQ in more than 9 cancer types. Because this analysis shows association rather than direction, both GABRQ-to-partner and partner-to-GABRQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by GABRQ-low versus GABRQ-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRQ→partner) and Y-score (partner→GABRQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Gamma-aminobutyric acid signaling pathway →	-0.272	-1.045	<.001	.001	3	10
SKIN	Regulation of protein modification by small protein conjugation or removal →	+0.057	+0.622	<.001	.004	3	9
OESOPHAGUS	Transcription initiation at RNA polymerase II promoter →	+0.074	+1.111	<.001	.002	3	8
STOMACH	Protein-DNA complex organization →	+0.051	+1.643	.001	.009	3	8
OESOPHAGUS	Alternative mRNA splicing, via spliceosome →	+0.102	+1.160	<.001	<.001	3	8
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.153	+1.012	<.001	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,883 associations by consensus.

Gamma-aminobutyric acid signaling pathway by GABRQ expression — OVARY

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