GABRQ

Across TCGA pan-cancer cohorts, GABRQ RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated GABRQ data layer compared with 7 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GABRQ RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GABRQ expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

KIRP, UVM, and KIRC are the cancer types where GABRQ RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.872	0.978	<.001	141	view →
UVM	DFS	Median	All	0.364	0.760	<.001	118	view →
KIRC	OS	Median	All	0.717	0.543	<.001	107	view →
STAD	OS	Median	II,III,IV	0.226	0.527	<.001	80	view →
BRCA	OS	Quartile	All	0.883	0.950	<.001	78	view →
ACC	OS	Tertile	II,III,IV	0.314	0.911	.002	72	view →
LIHC	DFS	Median	All	0.463	0.613	<.001	51	view →
UCEC	DFS	Quartile	All	0.544	0.697	.004	32	view →
UCS	OS	Median	II,III,IV	0.600	0.255	.020	26	view →
BLCA	DFS	Tertile	II,III,IV	0.258	0.411	.010	24	view →
COAD	DFS	Tertile	All	0.701	0.851	.004	16	view →
READ	OS	Quartile	All	1.000	0.889	.012	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

GABRQ–KIRP (OS)

Open the KIRP breakdown →