GABRQ

Across TCGA cell cohorts, GABRQ mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABRQ-associated genes across cancer lineages are KRTAP10-3, OR8B12, and OR8B4. Each is linked with GABRQ in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRQ-to-partner and partner-to-GABRQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-3 grouped by GABRQ-low versus GABRQ-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRQ→partner) and Y-score (partner→GABRQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KRTAP10-3 →	+0.032	+2.920	.001	.001	3	2
OVARY	OR8B12 →	+0.017	+4.807	<.001	.003	3	1
OVARY	OR8B4 →	+0.015	+4.807	<.001	.003	3	1
SKIN	ZIM3 →	+0.005	+3.700	<.001	.009	3	1
SKIN	CATSPERD →	+0.082	+3.263	<.001	.006	3	1
SKIN	OR2T11 →	+0.007	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

KRTAP10-3 by GABRQ expression — LARGE_INTESTINE

Explore this box plot interactively →