Across TCGA patient cohorts, GABRG3 mutation is significantly associated with the RNA expression of many other genes, with 4,948 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRG3-associated genes across cancer lineages are UBE2T, UBE2L3, and XRCC6. Each is linked with GABRG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GABRG3-to-partner and partner-to-GABRG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRG3→partner) and Y-score (partner→GABRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2T →	+0.636	+2.513	<.001	<.001	3	5
UCEC	UBE2L3 →	+0.374	+2.191	<.001	<.001	3	4
UCEC	XRCC6 →	+0.497	+2.191	<.001	<.001	3	4
UCEC	CDKN3 →	+0.764	+2.180	<.001	<.001	3	4
UCEC	PSMA3 →	+0.399	+1.914	<.001	<.001	3	4
UCEC	VAPA →	+0.333	+2.506	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

Exploration

GABRG3 survival (RNA) · tumor vs normal (RNA) · all GABRG3 data types