Across TCGA patient cohorts, GABRG3 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRG3-associated genes across cancer lineages are Cyclin-B1, TIGAR, and ATM. Each is linked with GABRG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GABRG3-to-partner and partner-to-GABRG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRG3→partner) and Y-score (partner→GABRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.644	+2.000	.001	.003	3	5
UCEC	TIGAR →	+0.126	+1.389	.019	.023	3	4
UCEC	ATM →	-0.577	-2.874	<.001	<.001	3	4
LUAD	cIAP →	+0.174	+2.584	<.001	.011	3	2
UCEC	GAPDH →	+0.411	+1.874	.030	.049	3	2
UCEC	JNK2 →	+0.233	+2.348	<.001	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

GABRG3 survival (RNA) · tumor vs normal (RNA) · all GABRG3 data types