GABRG1

Across TCGA patient cohorts, GABRG1 mutation is significantly associated with the RNA expression of many other genes, with 3,670 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRG1-associated genes across cancer lineages are CKAP2L, SLC35B1, and GCNT4. Each is linked with GABRG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GABRG1-to-partner and partner-to-GABRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CKAP2L grouped by GABRG1-low versus GABRG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRG1→partner) and Y-score (partner→GABRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CKAP2L →	+0.517	+2.687	.003	<.001	3	4
UCEC	SLC35B1 →	+0.377	+3.010	<.001	<.001	3	4
LUAD	GCNT4 →	-0.519	-2.169	.006	.003	3	4
UCEC	KCNJ15 →	-0.576	-1.733	.009	.001	3	3
UCEC	LSM12 →	+0.482	+1.499	<.001	.007	3	3
UCEC	POLR3K →	+0.415	+2.928	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

CKAP2L by GABRG1 expression — UCEC

Explore this box plot interactively →