GABRG1

Across TCGA pan-cancer cohorts, GABRG1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated GABRG1 data layer compared with 7 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher GABRG1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GABRG1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRC show a favorable association.

BLCA, PAAD, and KIRC are the cancer types where GABRG1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.196	0.454	<.001	129	view →
PAAD	OS	Median	All	0.517	0.280	.001	55	view →
KIRC	OS	Tertile	All	0.701	0.545	<.001	48	view →
STAD	OS	Tertile	All	0.437	0.635	.003	46	view →
KIRP	DFS	Quartile	II,III,IV	0.139	0.696	.005	44	view →
LGG	DFS	Median	All	0.820	0.653	<.001	40	view →
UCEC	DFS	Median	All	0.545	0.693	.002	32	view →
UVM	DFS	Tertile	All	0.350	0.807	.009	30	view →
CESC	DFS	Tertile	All	0.812	0.491	.003	30	view →
THYM	OS	Median	All	1.000	0.791	.012	22	view →
SCLC	OS	Tertile	All	0.462	0.896	.009	18	view →
COAD	DFS	Tertile	All	0.691	0.796	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

GABRG1–BLCA (OS)

Open the BLCA breakdown →