GABRB1

Across TCGA patient cohorts, GABRB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,994 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRB1-associated GO terms across cancer lineages are Cellular response to histamine, Steroid hormone mediated signaling pathway, and Lens fiber cell differentiation. Each is linked with GABRB1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GABRB1-to-partner and partner-to-GABRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to histamine grouped by GABRB1-low versus GABRB1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB1→partner) and Y-score (partner→GABRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Cellular response to histamine →	-0.106	-0.423	<.001	<.001	3	15
ESCA	Steroid hormone mediated signaling pathway →	+0.067	+0.490	<.001	<.001	3	15
THYM	Lens fiber cell differentiation →	+0.044	+0.159	<.001	<.001	3	14
KIRC	Non-motile cilium assembly →	+0.035	+0.181	<.001	<.001	3	13
ESCA	Mitochondrial transport →	+0.047	+0.299	<.001	<.001	3	13
STAD	Macromolecule depalmitoylation →	+0.079	+0.342	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,994 associations by consensus.

Cellular response to histamine by GABRB1 expression — LAML

Explore this box plot interactively →