GABRB1

Across TCGA patient cohorts, GABRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,898 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRB1-associated genes across cancer lineages are SNRPD3, SEZ6L, and SOX10. Each is linked with GABRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRB1-to-partner and partner-to-GABRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRB1 versus SNRPD3 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB1→partner) and Y-score (partner→GABRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.437	+0.565	<.001	.001	3	1
GBM	SEZ6L →	+1.518	+0.391	.001	.003	3	1
GBM	SOX10 →	+1.139	+0.486	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.240	+0.587	<.001	<.001	3	1
GBM	NEFH →	+1.498	+0.607	<.001	<.001	3	1
GBM	RASD2 →	+0.702	+0.600	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,898 associations by consensus.

GABRB1 vs SNRPD3 — GBM

Explore this scatter interactively →