GABRB1

Across TCGA cell cohorts, GABRB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 449 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GABRB1-associated GO terms across cancer lineages are Cellular response to histamine, Gamma-aminobutyric acid signaling pathway, and Negative regulation of stress-activated MAPK cascade. Each is linked with GABRB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GABRB1-to-partner and partner-to-GABRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to histamine grouped by GABRB1-low versus GABRB1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB1→partner) and Y-score (partner→GABRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cellular response to histamine →	-0.220	-0.988	<.001	.002	3	5
BONE	Gamma-aminobutyric acid signaling pathway →	-0.169	-0.567	.004	.009	2	5
BONE	Negative regulation of stress-activated MAPK cascade →	+0.117	+0.609	.001	.009	3	3
LUNG_NSCLC_LUAD	Renal system development →	-0.023	-0.180	.001	.002	3	3
LUNG_NSCLC_LUAD	Nephron development →	-0.056	-0.211	<.001	.004	3	3
LUNG_NSCLC_LUAD	Nephron epithelium development →	-0.035	-0.183	.008	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 449 associations by consensus.

Cellular response to histamine by GABRB1 expression — CNS

Explore this box plot interactively →