GABRA1

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GABRA1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,539 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GABRA1-associated genes across cancer lineages are GABRB2, GABRG2, and LINC01202. Each is linked with GABRA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both GABRA1-to-partner and partner-to-GABRA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRA1 versus GABRB2 in LGG, with a Pearson correlation of 0.97.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA1→partner) and Y-score (partner→GABRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LGGGABRB2 →+2.710+3.221<.001<.001318
LGGGABRG2 →+2.824+2.743<.001<.001314
LGGLINC01202 →+1.011+2.913<.001<.001314
LGGEPHA6 →+0.554+2.156<.001<.001314
PAADCDH10 →+1.429+0.233<.001<.001313
LGGCNKSR2 →+1.052+2.358<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,539 associations by consensus.

GABRA1 vs GABRB2 — LGG

Per-sample scatter of GABRA1 vs GABRB2 in LGG (Pearson r = 0.97).

Explore this scatter interactively →

Exploration