GABRA1

Across TCGA patient cohorts, GABRA1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,981 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRA1-associated genes across cancer lineages are YPEL1, SNRPD3, and MAPK1. Each is linked with GABRA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRA1-to-partner and partner-to-GABRA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRA1 versus YPEL1 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA1→partner) and Y-score (partner→GABRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.605	+0.670	.003	.003	3	1
GBM	SNRPD3 →	+0.534	+0.778	<.001	<.001	3	1
GBM	MAPK1 →	+0.354	+0.566	.006	.005	3	1
GBM	ESS2 →	+0.265	+0.464	.007	.005	3	1
GBM	SEZ6L →	+2.004	+0.691	<.001	<.001	3	1
GBM	SNU13 →	+0.375	+0.708	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,981 associations by consensus.

GABRA1 vs YPEL1 — GBM

Explore this scatter interactively →