GABRA1

Across TCGA cell cohorts, GABRA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 258 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GABRA1-associated GO terms across cancer lineages are Synaptic vesicle clustering, snRNA 3'-end processing, and Iron coordination entity transport. Each is linked with GABRA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GABRA1-to-partner and partner-to-GABRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle clustering grouped by GABRA1-low versus GABRA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA1→partner) and Y-score (partner→GABRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Synaptic vesicle clustering →	-0.186	-0.110	.002	.009	3	3
CNS	snRNA 3'-end processing →	+0.040	+0.124	<.001	.002	2	4
LUNG_SCLC	Iron coordination entity transport →	+0.090	+0.580	.004	.006	3	3
OVARY	Negative regulation of cation transmembrane transport →	-0.071	-0.111	.003	.007	3	3
OVARY	Positive regulation of double-strand break repair →	+0.053	+0.076	<.001	.007	3	3
OVARY	Positive regulation of monoatomic ion transmembrane transport →	-0.077	-0.119	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 258 associations by consensus.

Synaptic vesicle clustering by GABRA1 expression — OVARY

Explore this box plot interactively →