GABPA

Across TCGA patient cohorts, GABPA mutation is significantly associated with the RNA expression of many other genes, with 1,822 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABPA-associated genes across cancer lineages are RNA5SP248, MIR4710, and RN7SL478P. Each is linked with GABPA in more than 1 cancer types. Because this analysis shows association rather than direction, both GABPA-to-partner and partner-to-GABPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP248 grouped by GABPA-low versus GABPA-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPA→partner) and Y-score (partner→GABPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNA5SP248 →	+0.887	+4.533	<.001	.004	3	2
BLCA	MIR4710 →	+0.490	+4.497	<.001	.009	3	2
BLCA	RN7SL478P →	+0.295	+4.268	<.001	.008	3	2
LUAD	RPS6P4 →	+0.118	+5.279	<.001	.006	3	2
BLCA	MIR1284 →	+0.623	+4.208	<.001	.009	3	2
BLCA	RNU6-904P →	+0.417	+5.444	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,822 associations by consensus.

RNA5SP248 by GABPA expression — READ

Explore this box plot interactively →