G6PC

Across TCGA cell cohorts, G6PC RNA expression is significantly associated with the RNA expression of many other genes, with 1,001 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible G6PC-associated genes across cancer lineages are OTC, RNASE8, and SLC13A1. Each is linked with G6PC in more than 3 cancer types. Because this analysis shows association rather than direction, both G6PC-to-partner and partner-to-G6PC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G6PC versus OTC in PANCREAS, with a Pearson correlation of 1.00.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC→partner) and Y-score (partner→G6PC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OTC →	+1.067	+0.105	.001	.005	3	4
UPPER_AERODIGESTIVE_TRACT	RNASE8 →	+0.110	+0.045	<.001	.004	3	4
SOFT_TISSUE	SLC13A1 →	+0.038	+0.082	<.001	<.001	3	3
SOFT_TISSUE	KLHL40 →	+0.886	+0.053	.002	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	DDI1 →	+0.044	+0.060	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	CD209 →	+0.092	+0.060	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,001 associations by consensus.

G6PC vs OTC — PANCREAS

Explore this scatter interactively →