G2E3

Across TCGA cell cohorts, G2E3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,711 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible G2E3-associated GO terms across cancer lineages are Mitotic sister chromatid segregation, Mitotic spindle organization, and Centrosome cycle. Each is linked with G2E3 in more than 17 cancer types. Because this analysis shows association rather than direction, both G2E3-to-partner and partner-to-G2E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic sister chromatid segregation grouped by G2E3-low versus G2E3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (G2E3→partner) and Y-score (partner→G2E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.099	+1.137	.008	<.001	3	18
BLOOD_Myeloma	Mitotic spindle organization →	+0.109	+1.175	<.001	<.001	3	18
BREAST	Centrosome cycle →	+0.109	+1.126	<.001	<.001	3	18
URINARY_TRACT	Sister chromatid segregation →	+0.103	+1.006	<.001	<.001	3	18
URINARY_TRACT	Protein localization to condensed chromosome →	+0.201	+1.173	<.001	<.001	3	18
URINARY_TRACT	Nuclear division →	+0.088	+1.116	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,711 associations by consensus.

Mitotic sister chromatid segregation by G2E3 expression — OESOPHAGUS

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