Across TCGA cell cohorts, FZD9 mutation is significantly associated with the RNA expression of many other genes, with 404 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FZD9-associated genes across cancer lineages are OR6N1, TNP1, and ADIPOQ. Each is linked with FZD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD9-to-partner and partner-to-FZD9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD9→partner) and Y-score (partner→FZD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6N1 →	+0.271	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	TNP1 →	+0.160	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	ADIPOQ →	+0.029	+5.228	<.001	.005	3	1
BLOOD_Lymphoma	S100A7A →	+0.026	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR2AK2 →	+0.037	+4.191	.003	.007	3	1
LARGE_INTESTINE	DDHD1 →	+0.729	+3.364	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 404 associations by consensus.

Exploration

FZD9 survival (RNA) · tumor vs normal (RNA) · all FZD9 data types