FZD8

Across TCGA patient cohorts, FZD8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,388 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FZD8-associated proteins across cancer lineages are FERMT2, NES, and OSTF1_S213. Each is linked with FZD8 in more than 4 cancer types. Because this analysis shows association rather than direction, both FZD8-to-partner and partner-to-FZD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD8 versus FERMT2 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD8→partner) and Y-score (partner→FZD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FERMT2 →	+0.478	+0.742	<.001	<.001	3	5
GBM	NES →	+0.510	+0.739	<.001	<.001	3	4
GBM	OSTF1_S213 →	-0.388	-0.682	.004	.001	3	4
PDAC	PALM2AKAP2_S720 →	+0.415	+0.679	<.001	<.001	3	4
BRCA	ID4_S5 →	+1.463	+1.236	<.001	<.001	3	4
PDAC	SORBS3 →	+0.372	+0.497	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,388 associations by consensus.

FZD8 vs FERMT2 — HNSC

Explore this scatter interactively →