FZD7

Across TCGA patient cohorts, FZD7 protein abundance is significantly associated with the RNA expression of many other genes, with 5,870 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD7-associated genes across cancer lineages are PPFIBP1, TMEM158, and POGLUT2. Each is linked with FZD7 in more than 4 cancer types. Because this analysis shows association rather than direction, both FZD7-to-partner and partner-to-FZD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD7 versus PPFIBP1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD7→partner) and Y-score (partner→FZD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPFIBP1 →	+0.921	+0.908	<.001	<.001	3	5
BRCA	TMEM158 →	+1.693	+1.009	<.001	<.001	3	5
COAD	POGLUT2 →	+1.034	+0.654	.002	.004	3	4
COAD	SCT →	+1.607	+0.511	.002	.003	3	4
HNSC	SYNDIG1 →	+1.236	+0.771	<.001	<.001	3	4
LSCC	LAMA1 →	+1.548	+0.728	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,870 associations by consensus.

FZD7 vs PPFIBP1 — BRCA

Explore this scatter interactively →