FZD5

Across TCGA patient cohorts, FZD5 mutation is significantly associated with the RNA expression of many other genes, with 3,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FZD5-associated genes across cancer lineages are MIR6803, RN7SL803P, and BRDTP1. Each is linked with FZD5 in more than 2 cancer types. Because this analysis shows association rather than direction, both FZD5-to-partner and partner-to-FZD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by FZD5-low versus FZD5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD5→partner) and Y-score (partner→FZD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.144	+4.478	<.001	<.001	3	3
SKCM	RN7SL803P →	+0.117	+3.875	<.001	.006	3	3
BLCA	BRDTP1 →	+0.078	+6.444	<.001	.001	3	2
CESC	SFPQP1 →	+0.013	+4.020	<.001	.009	3	2
CESC	FGF12-AS1 →	+0.019	+4.247	<.001	.007	3	2
CESC	FMO10P →	+0.031	+3.891	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,053 associations by consensus.

MIR6803 by FZD5 expression — UCEC

Explore this box plot interactively →