FZD4

Across TCGA cell cohorts, FZD4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,073 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FZD4-associated genes across cancer lineages are PRSS23, SMIM1, and PCF11. Each is linked with FZD4 in more than 7 cancer types. Because this analysis shows association rather than direction, both FZD4-to-partner and partner-to-FZD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD4 versus PRSS23 in SKIN, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD4→partner) and Y-score (partner→FZD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PRSS23 →	+2.982	+1.097	<.001	<.001	3	8
BLOOD_Leukemia	SMIM1 →	+1.997	+0.644	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	PCF11 →	+1.142	+0.832	<.001	<.001	3	7
BLOOD_Leukemia	SKI →	+1.154	+0.913	<.001	<.001	3	7
LARGE_INTESTINE	TULP3 →	+0.971	+1.045	<.001	<.001	3	7
BONE	EPHB4 →	+1.447	+1.741	.006	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,073 associations by consensus.

FZD4 vs PRSS23 — SKIN

Explore this scatter interactively →