FZD4-DT

Across TCGA patient cohorts, FZD4-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,826 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FZD4-DT-associated proteins across cancer lineages are RBPJ, TUT7, and ISYNA1. Each is linked with FZD4-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both FZD4-DT-to-partner and partner-to-FZD4-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD4-DT versus RBPJ in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD4-DT→partner) and Y-score (partner→FZD4-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBPJ →	-0.304	-0.461	<.001	.002	3	4
GBM	TUT7 →	-0.365	-0.428	<.001	<.001	3	4
LSCC	ISYNA1 →	+0.547	+0.325	.001	.002	3	4
CCRCC	NIT1 →	+0.338	+0.561	<.001	<.001	3	4
BRCA	ARHGEF37_S251 →	+1.090	+0.521	<.001	<.001	3	4
GBM	UBE4A →	+0.216	+0.497	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,826 associations by consensus.

FZD4-DT vs RBPJ — BRCA

Explore this scatter interactively →