FZD3

Across TCGA patient cohorts, FZD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,320 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD3-associated proteins across cancer lineages are CCAR2, PCM1, and ARHGAP27. Each is linked with FZD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both FZD3-to-partner and partner-to-FZD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD3 versus CCAR2 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD3→partner) and Y-score (partner→FZD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCAR2 →	+0.331	+0.822	<.001	<.001	3	7
HNSC	PCM1 →	+0.401	+1.148	<.001	<.001	3	6
GBM	ARHGAP27 →	-0.200	-0.480	.006	.002	3	5
OV	XPO7 →	+0.285	+0.861	<.001	<.001	3	5
UCEC	STK10 →	-0.373	-0.758	.001	<.001	3	5
HNSC	TRIM21 →	-0.466	-1.059	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,320 associations by consensus.

FZD3 vs CCAR2 — OV

Explore this scatter interactively →