FZD3

Across TCGA patient cohorts, FZD3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,927 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FZD3-associated genes across cancer lineages are CHRDL1, PLA2G12A, and LCP1. Each is linked with FZD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD3-to-partner and partner-to-FZD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD3 versus CHRDL1 in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD3→partner) and Y-score (partner→FZD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHRDL1 →	-1.440	-0.557	<.001	<.001	3	2
UCEC	PLA2G12A →	+0.727	+0.696	<.001	<.001	3	2
UCEC	LCP1 →	-1.067	-0.605	.001	.001	3	2
UCEC	AOX1 →	-0.807	-0.521	<.001	.003	3	2
OV	SNCA →	-0.740	-0.380	.006	.002	3	2
UCEC	FPR3 →	-1.053	-0.656	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,927 associations by consensus.

FZD3 vs CHRDL1 — UCEC

Explore this scatter interactively →