FZD1

Across TCGA patient cohorts, FZD1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,683 significant associations in total. OV shows the largest number of these associations.

The most reproducible FZD1-associated genes across cancer lineages are AEBP1, ADAM12, and HMCN1. Each is linked with FZD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FZD1-to-partner and partner-to-FZD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD1 versus AEBP1 in OV, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD1→partner) and Y-score (partner→FZD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AEBP1 →	+2.349	+1.012	<.001	<.001	3	7
OV	ADAM12 →	+2.101	+1.184	<.001	<.001	3	7
OV	HMCN1 →	+1.165	+0.765	<.001	<.001	3	6
OV	COL1A1 →	+2.721	+0.954	<.001	<.001	3	6
OV	NKX3-2 →	+1.446	+1.234	<.001	<.001	3	6
BRCA	MRC2 →	+1.040	+0.587	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,683 associations by consensus.

FZD1 vs AEBP1 — OV

Explore this scatter interactively →