FZD1

Across TCGA patient cohorts, FZD1 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,510 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FZD1-associated proteins across cancer lineages are ITGAV, ITGB5, and PTK7. Each is linked with FZD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FZD1-to-partner and partner-to-FZD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD1 versus ITGAV in OV, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD1→partner) and Y-score (partner→FZD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGAV →	+0.615	+0.935	<.001	<.001	3	8
OV	ITGB5 →	+0.777	+1.048	<.001	<.001	3	8
BRCA	PTK7 →	+0.602	+0.741	<.001	<.001	3	8
OV	GPX8 →	+0.775	+1.134	<.001	<.001	3	7
UCEC	ITGB1 →	+0.505	+0.535	<.001	<.001	3	7
GBM	LTBP3 →	+0.629	+0.681	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,510 associations by consensus.

FZD1 vs ITGAV — OV

Explore this scatter interactively →