Across TCGA cell cohorts, FYB2 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FYB2-associated genes across cancer lineages are PCYT1B, GNAT1, and NLRP12. Each is linked with FYB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FYB2-to-partner and partner-to-FYB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FYB2→partner) and Y-score (partner→FYB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PCYT1B →	+0.970	+3.169	.001	.009	3	1
SKIN	GNAT1 →	+0.045	+2.546	.009	.002	3	1
SKIN	NLRP12 →	+0.058	+2.772	.001	.004	3	1
SKIN	SLC35F4 →	+0.052	+2.647	<.001	.001	3	1
SKIN	OR5AU1 →	+0.019	+2.773	.001	<.001	3	1
SKIN	OR10A2 →	+0.021	+2.546	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

FYB2 survival (RNA) · tumor vs normal (RNA) · all FYB2 data types