Across TCGA cell cohorts, FYB2 mutation is significantly associated with the mutation status of many other genes, with 1,428 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FYB2-associated genes across cancer lineages are ZNF573, LRP10, and EVC2. Each is linked with FYB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FYB2-to-partner and partner-to-FYB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FYB2→partner) and Y-score (partner→FYB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF573 →	+3.321	+2.459	.005	.005	1	3
SKIN	LRP10 →	+2.604	+2.133	.006	.006	1	3
OVARY	EVC2 →	+4.415	+4.977	.007	.007	1	3
SKIN	LHCGR →	+2.060	+1.943	.007	.007	1	3
OVARY	FAM131B →	+5.415	+5.415	.004	.004	1	3
OVARY	PYGL →	+5.415	+5.415	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,428 associations by consensus.

Exploration

FYB2 survival (RNA) · tumor vs normal (RNA) · all FYB2 data types