FXYD4

Across TCGA patient cohorts, FXYD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,036 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FXYD4-associated GO terms across cancer lineages are Mitochondrial electron transport, NADH to ubiquinone, Respiratory electron transport chain, and Oxidative phosphorylation. Each is linked with FXYD4 in more than 13 cancer types. Because this analysis shows association rather than direction, both FXYD4-to-partner and partner-to-FXYD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, NADH to ubiquinone grouped by FXYD4-low versus FXYD4-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD4→partner) and Y-score (partner→FXYD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Mitochondrial electron transport, NADH to ubiquinone →	+0.040	+0.814	<.001	<.001	3	14
DLBC	Respiratory electron transport chain →	+0.056	+0.220	.009	.008	1	14
HNSC	Oxidative phosphorylation →	+0.029	+0.195	<.001	<.001	3	11
HNSC	Proton motive force-driven ATP synthesis →	+0.030	+0.175	<.001	<.001	3	11
TGCT	ATP metabolic process →	+0.024	+0.829	<.001	<.001	3	11
KIRC	ATP synthesis coupled electron transport →	+0.035	+0.523	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,036 associations by consensus.

Mitochondrial electron transport, NADH to ubiquinone by FXYD4 expression — KIRC

Explore this box plot interactively →