FXYD4

Across TCGA patient cohorts, FXYD4 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FXYD4-associated genes across cancer lineages are aDC, cDC, and Adipocytes. Each is linked with FXYD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXYD4-to-partner and partner-to-FXYD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by FXYD4-low versus FXYD4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD4→partner) and Y-score (partner→FXYD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.075	+2.332	.042	.020	3	1
UCEC	cDC →	+0.194	+3.008	<.001	.019	3	1
UCEC	Adipocytes →	+0.024	+3.092	.008	.001	3	1
UCEC	DC →	+0.034	+3.688	<.001	.001	3	1
UCEC	pDC →	+0.050	+2.815	.039	.036	3	1
UCEC	Th2 cells →	+0.257	+2.177	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

aDC by FXYD4 expression — UCEC

Explore this box plot interactively →