FXYD1

Across TCGA cell cohorts, FXYD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,770 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FXYD1-associated GO terms across cancer lineages are Regulation of sodium ion export across plasma membrane, Positive regulation of sodium ion export across plasma membrane, and Regulation of protein processing. Each is linked with FXYD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FXYD1-to-partner and partner-to-FXYD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sodium ion export across plasma membrane grouped by FXYD1-low versus FXYD1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD1→partner) and Y-score (partner→FXYD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of sodium ion export across plasma membrane →	-0.302	-0.822	<.001	.004	3	7
SOFT_TISSUE	Positive regulation of sodium ion export across plasma membrane →	-0.302	-0.822	<.001	.004	3	7
BLOOD_Leukemia	Regulation of protein processing →	+0.049	+0.390	.004	.002	3	6
SOFT_TISSUE	Intracellular potassium ion homeostasis →	-0.200	-1.007	<.001	<.001	3	5
OVARY	Negative regulation of cholesterol efflux →	+0.171	+0.841	<.001	.001	3	5
OVARY	Regulation of sodium ion transmembrane transport →	-0.114	-0.914	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,770 associations by consensus.

Regulation of sodium ion export across plasma membrane by FXYD1 expression — SOFT_TISSUE

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