FUZ

Across TCGA cell cohorts, FUZ RNA expression is significantly associated with the go_rna of many other GO terms, with 4,683 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FUZ-associated GO terms across cancer lineages are Embryonic body morphogenesis, Regulation of base-excision repair, and Negative regulation of gene expression, epigenetic. Each is linked with FUZ in more than 13 cancer types. Because this analysis shows association rather than direction, both FUZ-to-partner and partner-to-FUZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic body morphogenesis grouped by FUZ-low versus FUZ-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUZ→partner) and Y-score (partner→FUZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Embryonic body morphogenesis →	+0.162	+2.262	.001	.001	3	14
BONE	Regulation of base-excision repair →	+0.114	+1.442	.001	.001	3	10
BLOOD_Leukemia	Negative regulation of gene expression, epigenetic →	+0.056	+1.322	<.001	<.001	3	10
BONE	Regulation of DNA repair →	+0.068	+1.201	<.001	<.001	3	10
SOFT_TISSUE	Transport along microtubule →	+0.034	+0.957	.003	.001	3	10
OESOPHAGUS	Primary neural tube formation →	+0.079	+1.952	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,683 associations by consensus.

Embryonic body morphogenesis by FUZ expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →