FUT8-AS1

Across TCGA pan-cancer cohorts, FUT8-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FUT8-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FUT8-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FUT8-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and MESO show a favorable association.

SKCM, KICH, and UVM are the cancer types where FUT8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.399	0.283	<.001	107	view →
KICH	DFS	Median	All	0.683	0.974	.001	84	view →
UVM	OS	Quartile	II,III,IV	0.684	0.975	.001	52	view →
MESO	OS	Median	III,IV	0.767	0.313	.004	47	view →
LGG	OS	Median	All	0.738	0.873	<.001	43	view →
BLCA	OS	Quartile	All	0.723	0.316	.007	36	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
BRCA	OS	Median	III,IV	0.951	0.855	.001	33	view →
KIRC	DFS	Quartile	All	0.727	0.846	.002	28	view →
ACC	DFS	Quartile	III,IV	0.618	0.106	.001	27	view →
OV	OS	Median	All	0.887	0.794	.005	26	view →
HNSC	DFS	Tertile	IV	0.743	0.581	.007	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FUT8-AS1–SKCM (OS)

Open the SKCM breakdown →