FUT8-AS1

Across TCGA pan-cancer cohorts, FUT8-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FUT8-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where FUT8-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FUT8-AS1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRP, BRCA, and LUAD are the cancer types where FUT8-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FUT8-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	+0.734	<.001	8	view →
BRCA	All	III,IV	+0.673	<.001	8	view →
LUAD	Female	II,III,IV	+0.779	<.001	7	view →
LUSC	All	All	+0.318	<.001	5	view →
KICH	Female	All	−0.468	.008	3	view →
COAD	All	All	+0.238	.021	3	view →
READ	Female	All	+0.676	.007	2	view →
UCEC	All	All	−0.562	.006	2	view →
HNSC	Male	IV	+0.403	.019	2	view →
CHOL	All	All	+0.496	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FUT8-AS1–KIRP

Open the KIRP breakdown →