FUT6

Across TCGA patient cohorts, FUT6 mutation is significantly associated with the RNA expression of many other genes, with 1,845 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUT6-associated genes across cancer lineages are SNORD114-14, UHRF1, and TSPY22P. Each is linked with FUT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUT6-to-partner and partner-to-FUT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-14 grouped by FUT6-low versus FUT6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT6→partner) and Y-score (partner→FUT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SNORD114-14 →	+0.447	+6.618	<.001	.001	3	2
UCEC	UHRF1 →	+0.646	+2.081	.004	.001	3	2
BRCA	TSPY22P →	+0.033	+7.471	<.001	.008	3	2
BRCA	AKR1B1P4 →	+0.054	+5.317	<.001	.006	3	2
SKCM	ALKBH6 →	+0.321	+2.591	.007	.006	3	2
SKCM	DAGLB →	+0.366	+3.208	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,845 associations by consensus.

SNORD114-14 by FUT6 expression — BLCA

Explore this box plot interactively →