FUT10

Across TCGA cell cohorts, FUT10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,358 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FUT10-associated GO terms across cancer lineages are Positive regulation of DNA damage checkpoint, Protein-DNA complex disassembly, and Aminoacyl-tRNA metabolism involved in translational fidelity. Each is linked with FUT10 in more than 10 cancer types. Because this analysis shows association rather than direction, both FUT10-to-partner and partner-to-FUT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA damage checkpoint grouped by FUT10-low versus FUT10-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT10→partner) and Y-score (partner→FUT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of DNA damage checkpoint →	+0.088	+0.778	<.001	<.001	3	11
BONE	Protein-DNA complex disassembly →	+0.144	+0.906	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.094	+0.813	.001	.001	3	10
BONE	RNA polymerase II transcription initiation surveillance →	+0.115	+0.930	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	tRNA transcription by RNA polymerase III →	+0.125	+0.854	.001	<.001	3	10
LIVER	Regulation of sterol biosynthetic process →	+0.103	+0.737	.006	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,358 associations by consensus.

Positive regulation of DNA damage checkpoint by FUT10 expression — OVARY

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