FUT10

Across TCGA pan-cancer cohorts, FUT10 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FUT10 data layer compared with 5 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher FUT10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FUT10 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

LIHC, KIRC, and HNSC are the cancer types where FUT10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.704	0.855	.001	70	view →
KIRC	DFS	Median	All	0.716	0.545	<.001	50	view →
HNSC	DFS	Tertile	III,IV	0.438	0.204	.004	35	view →
BLCA	OS	Quartile	All	0.320	0.603	.005	34	view →
COAD	DFS	Tertile	All	0.698	0.454	.009	24	view →
PRAD	DFS	Quartile	All	0.920	0.548	.003	22	view →
PAAD	OS	Quartile	All	0.295	0.586	.006	20	view →
LGG	OS	Median	All	0.756	0.871	<.001	19	view →
MESO	OS	Median	IV	0.323	0.827	.001	17	view →
ACC	DFS	Tertile	All	0.491	0.792	.002	16	view →
STAD	DFS	Tertile	IV	0.131	0.638	.021	15	view →
READ	OS	Median	II,III,IV	0.787	0.509	.008	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FUT10–LIHC (OS)

Open the LIHC breakdown →