FUT10

Across TCGA cell cohorts, FUT10 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FUT10-associated genes across cancer lineages are OR13J1, C20orf85, and OR1L4. Each is linked with FUT10 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUT10-to-partner and partner-to-FUT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13J1 grouped by FUT10-low versus FUT10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT10→partner) and Y-score (partner→FUT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR13J1 →	+0.136	+3.607	<.001	.004	3	2
SOFT_TISSUE	C20orf85 →	+0.086	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR1L4 →	+0.053	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR4D6 →	+0.035	+4.977	<.001	.002	3	1
SOFT_TISSUE	DRD5 →	+0.014	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR51L1 →	+0.027	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR13J1 by FUT10 expression — BLOOD_Leukemia

Explore this box plot interactively →