FUT1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FUT1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FUT1 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FUT1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FUT1 expression acts as an unfavorable survival marker.

GBM and SKCM are the cancer types where FUT1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMOSMedianAll0.0750.416.0116view →
SKCMDFSMedianII,III,IV0.1380.683.0106view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FUT1–GBM (OS)

Kaplan–Meier survival curve for FUT1 mutant vs wild-type samples in GBM.

Open the GBM breakdown →

Exploration