FUT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FUT1 mutation is significantly associated with the RNA expression of many other genes, with 1,118 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUT1-associated genes across cancer lineages are SYAP1, ETFDH, and TIPIN. Each is linked with FUT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FUT1-to-partner and partner-to-FUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYAP1 grouped by FUT1-low versus FUT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT1→partner) and Y-score (partner→FUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSYAP1 →+0.410+2.823.005.00133
UCECETFDH →+0.522+2.431<.001.00133
UCECTIPIN →+0.396+2.931.006<.00133
LIHCMIR3173 →+0.596+5.447<.001.00533
UCECGSR →+0.615+2.593.004.00633
UCECRNU6-879P →+0.306+1.774.008.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,118 associations by consensus.

SYAP1 by FUT1 expression — UCEC

Box plot of SYAP1 in FUT1-low vs FUT1-high samples in UCEC.

Explore this box plot interactively →

Exploration