FUT1

Across TCGA cell cohorts, FUT1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FUT1-associated genes across cancer lineages are ASB17, SIGLEC8, and GPR171. Each is linked with FUT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUT1-to-partner and partner-to-FUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by FUT1-low versus FUT1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT1→partner) and Y-score (partner→FUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
STOMACH	SIGLEC8 →	+0.005	+4.285	<.001	.007	3	1
STOMACH	GPR171 →	+0.023	+4.129	.005	.007	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1
LARGE_INTESTINE	ABCG4 →	+0.217	+3.451	.006	.005	3	1
LARGE_INTESTINE	ZNF648 →	+0.048	+3.743	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ASB17 by FUT1 expression — OVARY

Explore this box plot interactively →