FUCA2

Across TCGA pan-cancer cohorts, FUCA2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FUCA2 data layer compared with 30 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FUCA2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FUCA2 expression acts as an unfavorable survival marker.

LUAD, CCRCC, and HNSC are the cancer types where FUCA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.476	0.862	.005	18	view →
CCRCC	DFS	Median	III,IV	0.542	0.801	.015	13	view →
HNSC	OS	Quartile	II,III,IV	0.923	1.000	.026	7	view →
PDAC	OS	Median	II,III,IV	0.452	0.587	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FUCA2–LUAD (OS)

Open the LUAD breakdown →